Submission ID 93644
| Poster Code | HR-P-99 |
|---|---|
| Title of Abstract | Assessing Feasibility and Acceptability of Risk Reducing Strategies for Uterine Cancer |
| Abstract Submission | Introduction: Endometrial cancer (EC) is the most common gynaecological cancer in Canada. There have been no improvements in survival rates for EC in the past thirty years. The current method of diagnosis is through an invasive endometrial biopsy. No screening is currently recommended despite established risk factors that can be used to predict disease outcomes for EC early on. Objective: To evaluate the feasibility and acceptability of a screening protocol that identifies and tailors a risk reduction approach to individuals at high risk for EC. Methods: We will use known risk factors to identify postmenopausal individuals who are at the highest risk of developing EC. Those at high risk will undergo a non-invasive hormonal screening test to further identify those with endometrial proliferation, which could indicate the presence of endometrial disease. Those at high risk with endometrial proliferation will receive a biopsy and undergo a diet and exercise program to reverse known lifestyle risk factors. In addition, we will ask participants to self-collect samples by wearing tampons and using vaginal swabs that can be mailed from the participants homes to further advance molecular techniques for more non-invasive screening in the future. Anticipated Results: The proposed screening, intervention, and self-collection methods will be found acceptable and feasible by postmenopausal women in British Columbia. Conclusion: Early detection would allow for better disease outcomes due to earlier access to interventions and overall increasing rates of EC prevention. |
| Please indicate who nominated you | I was not nominated, however, my graduate program sent out an email encouraging students to submit an abstract. |
| What Canadian Institutes of Health Research (CIHR) institute is your research most closely aligned? | Cancer Research |
| What Canadian Institutes of Health Research (CIHR) pillar of health research does your research fall under? | Clinical |
| PDF of abstract | iCAM_submission_feb152023_RWOIMA.pdf 2023-02-16 at 15:43:42 |
| Presenter and Author(s) | Rachel Woima Rachel Woima Andrea Neilson Tim Rowe Mary Jung Dollina Dodani Sabine Halabi Malak Ibrahim Elise Abi Khalil Jessica McAlpine Aline Talhouk |
