Submission ID 93598
| Poster Code | HR-P-51 |
|---|---|
| Title of Abstract | Coronary heart disease attributable to psychosocial stressors at work among women and men |
| Abstract Submission | Background. Psychosocial stressors at work were shown to increase coronary heart disease (CHD) risk. However, the fraction of events attributable to these stressors among women and men has never been estimated using a prospective cohort. Objectives. To estimate the fraction of CHD events attributable to psychosocial stressors at work among women and men in a prospective cohort study. Methods. 6,465 white-collar workers without cardiovascular disease were followed for 15 years. Psychosocial stressors at work were measured according to the job strain and effort-reward imbalance (ERI) models. Incident CHD events were identified in medical databases with universal coverage. Attributable fractions (AFs) were estimated with Kaplan-Meier's method. Multiple imputations and inverse probability weights allowed controlling for selection and confounding. Results. Among 3,347 women, 208 had a first CHD event. AFs were 33.7% (95% CI: 5.9%; 61.5%) for passive, active jobs and high job strain exposure (vs low job strain), - 1.8% (95% CI: -10.5%; 7.0%) for ERI exposure and 21.7% (95 % CI: -14.8%; 58.3%) for combined exposure to both work stressors. Among 3,318 men, 461 had a first CHD event. AFs were 10.9% (95% CI: -5.7%; 27.5%) for passive, active jobs and high job strain exposure, 7.2% (95% CI: 1.6%; 12.8%) for ERI exposure and 22.4% (95 % CI: 2.1%; 42.8%) for combined exposure. Conclusions. Psychosocial stressors at work contributed up to one third of CHD events in women and more than a fifth in men. Early interventions on these work exposures may prevent a large number of CHD events. |
| Please indicate who nominated you | FMED FMED-Etudes Supérieures - Université Laval |
| What Canadian Institutes of Health Research (CIHR) institute is your research most closely aligned? | Population and Public Health |
| What Canadian Institutes of Health Research (CIHR) pillar of health research does your research fall under? | Population health |
| PDF of abstract | No file |
| Presenter and Author(s) | Mathilde Lavigne-Robichaud Mathilde Lavigne-Robichaud Xavier Trudel Denis Talbot Alain Milot chantal Brisson |
