Submission ID 118373

Issue/Objective Antimicrobial resistance (AMR) poses a serious threat to global health by compromising the effective treatment of infectious diseases across human, animal, and ecosystem health sectors. The One Health (OH) approach emphasizes multisectoral collaboration and is critical to equitably addressing AMR. Since the World Health Organization developed the Global Action Plan on AMR in 2015, 178 countries have developed national action plans focusing on AMR, with many emphasizing the role of OH governance. However, challenges remain in implementing OH governance effectively. In particular, understanding of how OH governance mechanisms can be effectively implemented across diverse institutional, social, economic, and political contexts remains limited
Methodology/Approach This mixed-methods project involved three phases: 1. A systematic scoping review of peer-reviewed and grey literature, synthesizing literature discussing the implementation of OH governance in diverse institutional, social, economic and political contexts; 2. Qualitative comparative analysis identifying key dimensions of context and OH governance mechanisms and how they may interact to support or undermine successful implementation of OH governance; and 3. Case study analysis focusing on a series of cases representing different combinations of contextual factors, incorporating document analysis and key informant interviews to assess how OH governance was implemented.
Results We identified key dimensions of country context that inform OH governance, including dimensions that impact agenda-setting, such as the burden of OH-relevant diseases and their risk factors, and connectivity to regional and global markets and policy discourse. We also identified contextual dimensions that are important for countries when designing and implementing novel, cross-sectoral public efforts such as OH governance, including resource endowment and the centralization of political authority. These contextual dimensions interact with dimensions of OH governance, including leadership, decision-making, coordination, resourcing, participation, and accountability. Context-appropriate OH governance can support better performance, which includes dimensions relating to governance process, including evidence-informed decision-making, inclusive participation, and improved capacity, as well as governance outcomes, such as stronger infrastructure, trained workforce, and effective disease prevention, detection and control.
Discussion/Conclusion This mixed-methods project aims to synthesize theoretical and empirical knowledge on effective, context-appropriate OH governance implementation in order to support different countries and regions in strengthening governance for AMR mitigation.
Presenters and affiliations Arne Ruckert Global Strategy Lab, York University
Chloe Clifford Astbury Global Strategy Lab, York University
Jaskeerat Singh Global Strategy Lab, York University
Suzanne Naro Global Strategy Lab, York University
Geneviève Boily-Larouche Global Strategy Lab, York University
Mathieu JP Poirier Global Strategy Lab, York University
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