| Issue/Objective |
A six-month course of Isoniazid Preventive Treatment is recommended, by the World Health Organization, for uninfected child contacts of persons with active tuberculosis (TB). Poor adherence may result in the exposed child becoming infected with TB, continued household and community transmission of TB as well as the risk of isoniazid resistance. This study determines the completion rates of IPT among child contacts at a TB directly observed treatment short course (DOTS) Centre in Lagos, Nigeria. |
| Methodology/Approach |
A secondary review of routinely collected health facility data spanning a 5-year period (2017 and 2022) was conducted. Age, gender, medication data were extracted from the IPT register using an extraction guide. Clients with incomplete records or who had transferred to another treatment centre were excluded. Clients who were recorded as receiving six months of treatment were classified as having completed the preventive treatment course, while receiving treatment for less than six months were classified as not completing treatment. Descriptive and bivariate data analysis were performed. |
| Results |
A 100 child contacts records were included. All were aged less than 6 years in line with eligibility for IPT, about one in four were 5 years old and majority were females (52%). Only 56% completed the IPT course, 41% of those that did not complete their dose were lost to follow up after the first month of treatment. Age and gender were not associated with IPT completion rate. |
| Discussion/Conclusion |
IPT completion was low, loss to follow up was highest after the first month of treatment increasing the risk of treatment default and tendency for antimicrobial resistance. |
| Presenters and affiliations |
Babatunde Odugbemi Dahdaleh Institute for Global Health Research, York University |