Submission ID 116445
| Issue/Objective | The Sub-Saharan Africa region has the greatest number of people eligible to receive antiretroviral treatment (ART). Consistency on antiretroviral therapy (ART) remains the most effective intervention in the global HIV response and has proven an effective for people living with HIV (PLHIV). Understanding the factors associated with interrupting antiretroviral therapy (ART) is therefore critical for designing client-centered services to ensure optimal outcomes. In Eswatini, Young Heroes is implementing an HIV program that aims to avert new HIV infections in children and youth and improve treatment outcomes for children and adolescents living with HIV (C/ALHIV: 0-19 Years) with HIV prevention and impact mitigation interventions that prevents new HIV infections and reduce vulnerability. Aim: To assess predictors of treatment interruption amongst Sabelo Sensha enrolled CALHIVs in Eswatini. |
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| Methodology/Approach | The project provides treatment adherence support and referrals to CALHIVs through trained community cadres (HVs) at both community and health facility levels. |
| Results | Overall, 1597 patients were on ART and 329 (20%) patients had ART interruptions. Retention at 1, 3, 6, 9, and 12 months was 87%, 83%, 79%, 76%, and 69%, respectively. From regression analysis, refiling in rural areas (p = 0.003), being an older CALHIV (15-17 years) (p < 0.005), and residing outside the clinic catchment area (p = 0.02) were major contributors of treatment interruption. |
| Discussion/Conclusion | Treatment interruption was common amongst the CALHIVs but can be improved by focusing on supporting elder CALHIVs (15+ years), CALHIV refiling in rural areas and providing client-centred HIV services for those who live further from clinics. |
| Presenters and affiliations | Themba Matsebula Young Heroes |
